The nucleus of the cell holds our genetic material and is a vital part of our cell. Apart from what they carry, how they look also plays a crucial role in diagnosing many diseases. In a recent study, researchers at the Indian Institute of Science (IISc), Bengaluru, have developed a mechanical model to quantify the shape of the nucleus and predict the biochemistry within a cell. They have used this model to show how Hepatitis C virus changes the nuclear mechanics of cells affected by it. This study is published in the Biophysical Journal.

Antimicrobials, a class of drugs used in humans and animals to treat diseases caused by bacteria, fungi, and parasites serve as a proxy for good hygiene and make up for the poor husbandry practices in animal farms in low and middle-income countries around the world. However, this dereliction comes with a considerable cost wherein, the overuse of these drugs has led to these microbes developing resistance against the very same drugs used to kill them.  Antimicrobial resistance (AMR) in humans is linked to several animals, especially those that are raised for food. Despite this knowledge, it has received little attention in the world of animal science. A new study, published in the journal Science, has mapped the global trends of antimicrobial resistance in farm animals, with particular focus on developing countries, including India. 

Antibiotics, drugs used to treat bacterial infections, have been pivotal in curing many bacterial diseases since its discovery in 1928. However, an emerging threat to using them is the rise of bacterial strains that are resistant to antibiotics. In a recent study, a team of researchers have used Drug Resistance Index (DRI) to measure the effectiveness of antibiotics against specific bacteria.

The differences in a child’s response to visual changes could point beyond how the brain functions, how it remembers its surroundings and detects changes. It could also indicate the parents education level and their economic status, says a new study. The study, published in the journal Developmental Science, looks into how children from disadvantaged backgrounds perceive visual changes.

In a press announcement released yesterday, India has now joined 16 other countries as a Member of the Global Antimicrobial Resistance (AMR) Research and Development (R&D) Hub. For a country that ranks the highest in antibacterial resistance, this move expands global partnership opportunities to address challenges and improve collaboration in addressing the growing epidemic of antimicrobial resistance.

The Indian krait is undoubtedly the deadliest of all venomous snakes in the country, and possesses the most lethal concoction of poisons. In a study, a multi-institute research team, led by the Translational Health Science and Technology Institute (THSTI), Faridabad, have designed a synthetic antivenom with a nucleic acid aptamer which can diagnose Indian krait bites accurately and effectively.

India, the world’s capital of diabetes, has an escalating diabetes epidemic. Diabetes, a non-communicable disease, affects about 8.7% Indians today, and this number is predicted to hit 70 million by 2025 and 80 million by 2030. Although the exact reasons for this rapid rise in diabetes in the country are not yet clear, experts blame it on multiple factors. In a recent study, researchers from the USA, Germany and India have investigated the status of diabetic care among Indian adults. The findings, published in the journal BMC Medicine, present a grim picture of diabetes management in different states and socio-demographic groups in India.

Visceral leishmaniasis, or kala-azar, is an insidious disease that affects thousands of people every year. This illness can be fatal, if not diagnosed and treated on time. However, despite best efforts, India still lags behind in eliminating this disease completely. A recent study published in the journal PLOS Neglected Tropical Diseases has investigated the factors that lead to the delayed diagnosis and treatment of kala-azar.

Researchers from Savitribai Phule Pune University have identified two strains of fungi, Aspergillus terreus and Aspergillus sydowii, which can degrade polythene under laboratory conditions.

Researchers from Singapore, Thailand and the USA, have created an antidiabetic medicine using extracts from Withania coagulans, commonly known as the Indian Rennet or paneer dodi.